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Table of Contents & Sample Chapter
This fourth volume in Anton C. de Groot’s authoritative series is a comprehensive reference dedicated to systemic drugs that cause delayed-type (type IV) cutaneous hypersensitivity reactions and occupational allergic contact dermatitis. It systematically documents all known systemic drugs implicated in these reactions, combining rigorous clinical detail with extensive literature review. Designed for clinicians and researchers dealing with complex drug allergies, the book serves as a definitive resource for understanding mechanisms, diagnosis, and clinical relevance of allergic cutaneous drug reactions.
Key Features
Monographs covering all 507 systemic drugs known to cause delayed allergic cutaneous drug reactions and/or occupational allergic contact dermatitis
Detailed sections for each drug including identification, occupational relevance, and type IV hypersensitivity reactions confirmed by patch testing
Comprehensive coverage of clinical reaction patterns such as maculopapular eruptions, AGEP, SDRIFE, fixed drug eruption, DRESS, and photosensitivity
Separate chapters reviewing the full spectrum of allergic cutaneous drug reactions and current diagnostic testing methods
Inclusion of immediate contact reactions (contact urticaria) caused by systemic drugs
Analysis of drugs causing delayed-type hypersensitivity exclusively through cross-reactivity
Extensive literature synthesis, including data not easily accessible through standard database searches
Precise chemical and regulatory details: IUPAC names, synonyms, CAS and EC numbers, chemical structures, Merck Index references, and patch-testing guidance
Highly valuable for dermatologists, allergists, occupational physicians, and clinicians involved in drug allergy diagnosis and management