Transformation of Human Diploid Fibroblasts: Molecular and Genetic Mechanisms

By George E. Milo, Bruce C. Casto

Carcinogen-Cell Interactions provides a comprehensive exploration of how cells respond to carcinogenic insults and the molecular mechanisms underlying cellular transformation. This work integrates current research and reviews to offer a detailed understanding of the biology of human cell neoplasia.

Key Features:

• Regulation of Normal Cell Proliferation: Explains mechanisms controlling cell growth and division.
• Cellular Responses to Carcinogen Damage: Details how cells detect, repair, or respond to DNA and structural damage caused by carcinogens.
• Molecular and Genomic Changes: Explores structural DNA modifications, genomic instability, and their role in malignant transformation.
• Insights into Malignant Conversion: Examines pathways and conditions that convert normal human fibroblasts into cancerous cells.
• Up-to-Date Reviews: Includes current literature references and critical analyses from leading investigators.
• Target Audience: Ideal for advanced students and professionals in genetic toxicology, molecular biology, cancer biology, and related fields.

Product Details

• Publisher ‏ : ‎ CRC Press; 1st edition (May 15, 1990)
• Language ‏ : ‎ English
• ISBN-10 ‏ : ‎ 0849349567
• ISBN-13 ‏ : ‎ 978-0849349560